Gao, L., Kantar, M. B., Moxley, D., Ortiz-Barrientos, D. & Rieseberg, L. H. Crop adaptation to local weather change: an evolutionary perspective. Mol. Plant 16, 1518–1546 (2023).
Dong, Y. et al. Twin domestications and origin of traits in grapevine evolution. Science 379, 892–901 (2023).
Google Scholar
Lacombe, T. et al. Massive-scale parentage evaluation in an prolonged set of grapevine cultivars (Vitis vinifera L). Theor. Appl. Genet. 126, 401–414 (2013).
Google Scholar
Magris, G. et al. The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes. Nat. Commun. 12, 7240 (2021).
Google Scholar
OIV. Focus OIV 2017: Distribution of the World’s Grapevine Varieties. 54 (OIV, 2017).
Barker, J. State of the Vine and Wine Sector (OIV, 2024).
Boursiquot, J.-M., Yobrégat, O. & Lacombe, T. Estimating the grapevine cultivated biodiversity: indices for an goal analysis. OENO One 59, https://doi.org/10.20870/oeno-one.2025.59.1.8122 (2025).
Muthmann, R. & Nadin, P. The Use of Plant Safety Merchandise within the European Union (European Fee, Luxembourg, 2007).
Trapp, O. et al. Extra sustainability in Europe’s vineyards–Utilizing resistant grapevine varieties to scale back the enter of pesticides. Vegetation Individuals, Planet 7, 1621–1628 (2025).
Vezzulli, S. et al. in Genomic Designing for Biotic Stress Resistant Fruit Crops (ed Chittaranjan Kole) 87–255 (Springer Worldwide Publishing, 2022).
Pertot, I. et al. A essential evaluate of plant safety instruments for lowering pesticide use on grapevine and new views for the implementation of IPM in viticulture. Crop Prot. 97, 70–84 (2017).
Google Scholar
Koledenkova, Ok. et al. Plasmopara viticola the causal agent of downy mildew of grapevine: from its taxonomy to illness administration. Entrance. Microbiol. 13, 889472 (2022).
Google Scholar
Sambucci, O., Alston, J. M., Fuller, Ok. B. & Lusk, J. The pecuniary and nonpecuniary prices of powdery mildew and the potential worth of resistant grape varieties in California. Am. J. Enol. Vitic. 70, 177–187 (2019).
Szabó, M. et al. Black rot of grapes (Guignardia bidwellii)—A complete overview. Horticulturae 9, 130 (2023).
Pirrello, C. et al. Emergent Ascomycetes in viticulture: an interdisciplinary overview. Entrance. Plant Sci. 10, 1394 (2019).
Google Scholar
Jacometti, M., Wratten, S. & Walter, M. Options to artificial fungicides for Botrytis cinerea administration in vineyards. Aust. J. Grape Wine Res. 16, 154–172 (2010).
Google Scholar
Herzog, Ok., Wind, R. & Töpfer, R. Impedance of the grape berry cuticle as a novel phenotypic trait to estimate resistance to Botrytis cinerea. Sensors 15, 12498–12512 (2015).
Fontaine, F. et al. Grapevine trunk illness. A evaluate. OIV publications, https://www.oiv.int/websites/default/recordsdata/2022-09/trunk-diseases-oiv-2016_en.pdf (2016).
Nerva, L. et al. The hidden world inside vegetation: metatranscriptomics unveils the complexity of wooden microbiomes. J. Exp. Bot. 73, 2682–2697 (2022).
Google Scholar
Fouillet, E. et al. Decreasing pesticide use in vineyards. Proof from the evaluation of the French DEPHY community. Eur. J. Agron. 136, 126503 (2022).
Barmettler, E. et al. Double the difficulty: excessive ranges of each artificial pesticides and copper in winery soils. Environ. Pollut. 375, 126356 (2025).
Google Scholar
Van Leeuwen, C. & Seguin, G. The idea of terroir in viticulture. J. Wine Res. 17, 1–10 (2006).
Tscholl, S. et al. Local weather resilience of European wine areas. Nat. Commun. 15, 6254 (2024).
Google Scholar
Jones, G. V., White, M. A., Cooper, O. R. & Storchmann, Ok. Local weather change and world wine high quality. Clim. Change 73, 319–343 (2005).
Hannah, L. et al. Local weather change, wine, and conservation. Proc. Natl. Acad. Sci. USA. 110, 6907–6912 (2013).
Google Scholar
Marín, D. et al. Challenges of viticulture adaptation to world change: tackling the difficulty from the roots. Aust. J. Grape Wine Res. 27, 8–25 (2021).
Döring, J., Collins, C., Frisch, M. & Kauer, R. Natural and biodynamic viticulture have an effect on biodiversity and properties of vine and wine: a scientific quantitative evaluate. Am. J. Enol. Vitic. 70, 221–242 (2019).
Reganold, J. P. & Wachter, J. M. Natural agriculture within the twenty-first century. Nat. Vegetation 2, 15221 (2016).
Google Scholar
Komárek, M., Čadková, E., Chrastný, V., Bordas, F. & Bollinger, J.-C. Contamination of winery soils with fungicides: a evaluate of environmental and toxicological points. Environ. Int. 36, 138–151 (2010).
Google Scholar
Delrot, S. et al. in Genomic Designing of Local weather-Good Fruit Crops, 157–270 (Springer, 2020).
Moffa, L. et al. CRISPR/Cas9-driven double modification of grapevine MLO6-7 imparts powdery mildew resistance, whereas enhancing of NPR3 augments powdery and downy mildew tolerance. Plant J. 122, e17204 (2025).
Google Scholar
Gambino, G. et al. Genome enhancing of a recalcitrant wine grape genotype by lipofectamine-mediated supply of CRISPR/Cas9 ribonucleoproteins to protoplasts. Plant J. 119, 404–412 (2024).
Shahbaz, U. et al. Lowered stomatal density improves water-use effectivity in grapevine below local weather situations of decreased water availability. Plant Cell Rep. 44, https://doi.org/10.1007/s00299-025-03577-9 (2025).
Giacomelli, L. et al. Simultaneous enhancing of two DMR6 genes in grapevine ends in lowered susceptibility to downy mildew. Entrance. Plant Sci. 14, https://doi.org/10.3389/fpls.2023.1242240 (2023).
Moine, A. et al. Exploiting somaclonal variability to extend drought stress tolerance in grapevine. https://doi.org/10.5281/zenodo.15944748 (2025).
Schumacher, S., Mertes, C., Kaltenbach, T., Bleyer, G. & Fuchs, R. A technique for phenotypic analysis of grapevine resistance in relation to phenological growth. Sci. Rep. 14, https://doi.org/10.1038/s41598-023-50666-4 (2024).
Agnoli, L., Vasileiou, E. & Demaria, F. Limitations and drivers within the adoption of recent genomic strategies for grapevines. Wine Econ. Coverage 14, 25-39 (2025).
Dressler, M. Assembly market and societal ambitions with new sturdy grape varietals: sustainability, the inexperienced deal, and wineries’ resilience. Agriculture 14, https://doi.org/10.3390/agriculture14122138 (2024).
Wolkovich, E. M., García de Cortázar-Atauri, I., Morales-Castilla, I., Nicholas, Ok. A. & Lacombe, T. From Pinot to Xinomavro on the earth’s future wine-growing areas. Nat. Clim. Change 8, 29–37 (2018).
van Leeuwen, C. et al. Local weather change impacts and diversifications of wine manufacturing. Nat. Rev. Earth Environ. 5, 258–275 (2024).
Google Scholar
Cook dinner, B. I. & Wolkovich, E. M. Local weather change decouples drought from early wine grape harvests in France. Nat. Clim. Change 6, 715–719 (2016).
Fraga, H., García de Cortázar Atauri, I., Malheiro, A. C. & Santos, J. A. Modelling local weather change impacts on viticultural yield, phenology and stress circumstances in Europe. Glob. Change Biol. 22, 3774–3788 (2016).
Morales-Castilla, I. et al. Variety buffers winegrowing areas from local weather change losses. Proc. Natl. Acad. Sci. USA. 117, 2864–2869 (2020).
Google Scholar
Resco, P., Iglesias, A., Bardají, I. & Sotés, V. Exploring adaptation selections for grapevine areas in Spain. Reg. Environ. Change 16, 979–993 (2016).
Google Scholar
Sgubin, G. et al. The danger of tardive frost injury in French vineyards in a altering local weather. Agric. For. Meteorol. 250, 226–242 (2018).
Mosedale, J. R., Abernethy, Ok. E., Good, R. E., Wilson, R. J. & Maclean, I. M. Local weather change impacts and adaptive methods: classes from the grapevine. Glob. Change Biol. 22, 3814–3828 (2016).
Salinari, F. et al. Downy mildew (Plasmopara viticola) epidemics on grapevine below local weather change. Glob. Change Biol. 12, 1299–1307 (2006).
Caffarra, A., Rinaldi, M., Eccel, E., Rossi, V. & Pertot, I. Modelling the affect of local weather change on the interplay between grapevine and its pests and pathogens: European grapevine moth and powdery mildew. Agric. Ecosyst. Environ. 148, 89–101 (2012).
Reineke, A. & Thiéry, D. Grapevine insect pests and their pure enemies within the age of world warming. J. Pest Sci. 89, 313–328 (2016).
Google Scholar
Myles, S. et al. Genetic construction and domestication historical past of the grape. Proc. Natl. Acad. Sci. USA. 108, 3530–3535 (2011).
Google Scholar
De Andrés, M. et al. Genetic variety of untamed grapevine populations in Spain and their genetic relationships with cultivated grapevines. Mol. Ecol. 21, 800–816 (2012).
Google Scholar
Duchêne, E. How can grapevine genetics contribute to the difference to local weather change? OENO One 50, 113–124 (2016).
Bernardo, S. et al. Root system ideotypes: what’s the potential for breeding drought-tolerant grapevine rootstocks? J. Exp. Bot. 76, 2970–2984 (2025).
Google Scholar
Ollat, N. et al. in Grapevine in a Altering Setting 68–108 (Wiley, 2015).
Chisholm, S. T., Coaker, G., Day, B. & Staskawicz, B. J. Host-microbe interactions: shaping the evolution of the plant immune response. Cell 124, 803–814 (2006).
Google Scholar
Jones, J. D., Staskawicz, B. J. & Dangl, J. L. The plant immune system: from discovery to deployment. Cell 187, 2095–2116 (2024).
Google Scholar
Merdinoglu, D., Schneider, C., Prado, E., Wiedemann-Merdinoglu, S. & Mestre, P. Breeding for sturdy resistance to downy and powdery mildew in grapevine. OENO One 52, 203–209 (2018).
Possamai, T. & Wiedemann-Merdinoglu, S. Phenotyping for QTL identification: a case examine of resistance to Plasmopara viticola and Erysiphe necator in grapevine. Entrance. Plant Sci. 13, 930954 (2022).
Hoffmann, S. et al. Resistance to Erysiphe necator within the grapevine ‘Kishmish vatkana’ is managed by a single locus by means of restriction of hyphal development. Theor. Appl. Genet. 116, 427–438 (2008).
Google Scholar
Possamai, T. et al. Development of a high-density genetic map and detection of a significant QTL of resistance to powdery mildew (Erysiphe necator Sch.) in Caucasian grapes (Vitis vinifera L). BMC Plant Biol. 21, 528 (2021).
Google Scholar
Sargolzaei, M. et al. Rpv29, Rpv30 and Rpv31: three novel genomic loci related to resistance to Plasmopara viticola in Vitis vinifera. Entrance. Plant Sci. 11, 2020 (2020).
Mundt, C. C. Pyramiding for resistance sturdiness: principle and apply. Phytopathology 108, 792–802 (2018).
Google Scholar
Wang, Y., Ding, Ok., Li, H., Kuang, Y. & Liang, Z. Biography of Vitis genomics: latest advances and potential. Hortic. Res. 11, https://doi.org/10.1093/hr/uhae128 (2024).
Nicotra, A. B. et al. Plant phenotypic plasticity in a altering local weather. Developments Plant Sci. 15, 684–692 (2010).
Google Scholar
Lereboullet, A.-L., Beltrando, G. & Bardsley, D. Ok. Socio-ecological adaptation to local weather change: a comparative case examine from the Mediterranean wine business in France and Australia. Agric. Ecosyst. Environ. 164, 273–285 (2013).
Naulleau, A., Gary, C., Prévot, L. & Hossard, L. Evaluating methods for adaptation to local weather change in grapevine manufacturing–A scientific evaluate. Entrance. Plant Sci. 11, 2020 (2021).
Crossa, J. et al. Genomic choice in plant breeding: strategies, fashions, and views. Developments Plant Sci. 22, 961–975 (2017).
Brault, C. et al. Throughout-population genomic prediction in grapevine opens up promising prospects for breeding. Hortic. Res. 9, uhac041 (2022).
Google Scholar
Brault, C. et al. Enhancing grapevine breeding effectivity by means of genomic prediction and choice index. G3 Genes|Genomes|Genet. 14, jkae038 (2024).
Google Scholar
Miclot, A.-S. et al. 4 years of monitoring of disease-resistant grapevine varieties in French vineyards. In BIO Internet of Conferences Vol. 50, 02008 (2022).
Montaigne, E., Coelho, A. & Zadmehran, S. A complete financial examination and prospects on innovation in new grapevine varieties coping with world warming and fungal illnesses. Sustainability 13, 13254 (2021).
Zachmann, L., McCallum, C. & Finger, R. Determinants of the adoption of fungus-resistant grapevines: proof from Switzerland. J. Wine Econ. 19, 232–264 (2024).
Vecchio, R., Pomarici, E., Giampietri, E. & Borrello, M. Shopper acceptance of fungus-resistant grape wines: proof from Italy, the UK, and the USA. PLoS ONE 17, e0267198 (2022).
Google Scholar
EFSA-Panel-on-Genetically-Modified-Organisms Scientific opinion addressing the security evaluation of vegetation developed by means of cisgenesis and intragenesis. EFSA J. 10, 2561 (2012).
EFSA-Panel-on-Genetically-Modified-Organisms et al. Standards for danger evaluation of vegetation produced by focused mutagenesis, cisgenesis and intragenesis. EFSA J. 20, e07618 (2022).
Dalla Costa, L. et al. Environment friendly heat-shock elimination of the selectable marker gene in genetically modified grapevine. Plant Cell Tissue Organ Cult. 124, 471–481 (2016).
Google Scholar
Nerva, L. et al. The position of Italy in the usage of superior plant genomic strategies on fruit timber: cutting-edge and future views. Int. J. Mol. Sci. 24, 977 (2023).
Google Scholar
Cardi, T. Cisgenesis and genome enhancing: combining ideas and efforts for a wiser use of genetic assets in crop breeding. Plant Breed. 135, 139–147 (2016).
Google Scholar
Tricoli, D. M. & Debernardi, J. M. An environment friendly protoplast-based genome enhancing protocol for Vitis species. Hortic. Res. 11, uhad266 (2024).
Google Scholar
Najafi, S., Bertini, E., D’Incà, E., Fasoli, M. & Zenoni, S. DNA-free genome enhancing in grapevine utilizing CRISPR/Cas9 ribonucleoprotein complexes adopted by protoplast regeneration. Hortic. Res. 10, uhac240 (2023).
Google Scholar
Nuzzo, F., Gambino, G. & Perrone, I. Unlocking grapevine in vitro regeneration: points and views for genetic enchancment and useful genomic research. Plant Physiol. Biochem. 193, 99–109 (2022).
Google Scholar
Lassoued, R., Phillips, P. W., Macall, D. M., Hesseln, H. & Smyth, S. J. Professional opinions on the regulation of plant genome enhancing. Plant Biotechnol. J. 19, 1104–1109 (2021).
Google Scholar
Gaj, M. D. Elements influencing somatic embryogenesis induction and plant regeneration with specific reference to Arabidopsis thaliana (L.) Heynh. Plant Development Regul. 43, 27–47 (2004).
Google Scholar
Larkin, P. J. & Scowcroft, W. R. Somaclonal variation—a novel supply of variability from cell cultures for plant enchancment. Theor. Appl. Genet. 60, 197–214 (1981).
Google Scholar
Leisner, C. P., Potnis, N. & Sanz-Saez, A. Crosstalk and trade-offs: plant responses to local weather change-associated abiotic and biotic stresses. Plant Cell Environ. 46, 2946–2963 (2023).
Google Scholar
Callipo, P. et al. Harnessing clonal variety in grapevine: from genomic insights to trendy breeding purposes. Theor. Appl. Genet. 138, 196 (2025).
Google Scholar
Torregrosa, L. et al. Origins and penalties of somatic variation in grapevine. Genet. Genom. Breed. Grapes 68, 92 (2011).
Fortes, A. M. & Gallusci, P. Plant stress responses and phenotypic plasticity within the epigenomics period: views on the grapevine state of affairs, a mannequin for perennial crop vegetation. Entrance. Plant Sci. 8, 82 (2017).
Google Scholar
Carvalho, L. C. et al. Intra-varietal variability for abiotic stress tolerance traits within the grapevine selection Arinto. Vegetation 14, 2480 (2025).
Google Scholar
Rossi, V., Caffi, T., Salotti, I. & Fedele, G. Sharing decision-making instruments for pest administration could foster implementation of Built-in Pest Administration. Meals Secur. 15, 1459–1474 (2023).
Sandrini, M. et al. Microbial consortia inoculants otherwise form ecophysiological and systemic defence responses of field-grown grapevine cuttings. Plant Stress 14, 100686 (2024).
Google Scholar
Nerva, L. et al. Breeding towards improved ecological plant–microbiome interactions. Developments Plant Sci. 27, 1134–1143 (2022).
Google Scholar
Moran, N. A. & Sloan, D. B. The hologenome idea: useful or hole? PLoS Biol. 13, e1002311 (2015).
Google Scholar
Golicic, S. L. Adjustments in sustainability within the world wine business. Int. J. Wine Bus. Res. 34, 392–409 (2021).
García-Cortijo, M. C., Ferrer, J. R., Castillo-Valero, J. S. & Pinilla, V. The drivers of the sustainability of Spanish wineries: assets and capabilities. Sustainability 13, 10171 (2021).
Ouvrard, S., Jasimuddin, S. M. & Spiga, A. Does sustainability push to reshape enterprise fashions? Proof from the European wine business. Sustainability 12, 2561 (2020).
Casali, G. L., Perano, M., Presenza, A. & Abbate, T. Does innovation propensity affect wineries’ distribution channel selections? Int. J. Wine Bus. Res. 30, 446–462 (2018).
Sánchez-Pérez, M., Estrella-Ramón, A., Segovia-López, C. & Marín-Carrillo, M. B. Multichannel retailing and shopper behaviour: technique design and implementation. Int. J. Appl. Behav. Econ. 3, 17–39 (2014).
Granata, J., Aytaç, B. & Roubaud, D. Innovation developments within the wine business: a journey from the amphorae of previous to the California wine cluster. Int. J. Entrep. Small Bus. 36, 249–255 (2019).
Hira, A., Giest, S. & Howlett, M. Explaining the success of clusters: a framework for the examine of world wine business dynamics. in What Makes Clusters Aggressive – Circumstances from the World Wine Business (ed A. Hira) (McGill-Queen’s College Press, 2013).
Calliera, M. et al. Multi-actor strategy and engagement technique to advertise the adoption of finest administration practices and a sustainable use of pesticides for groundwater high quality enchancment in hilly vineyards. Sci. Complete Environ. 752, 142251 (2021).
Google Scholar
Meloni, G. & Swinnen, J. The political economic system of European wine laws. J. Wine Econ. 8, 244–284 (2013).
Espinoza, A. F., Hubert, A., Franc, C., Giraud-Heraud, E. & Raineau, Y. Resistant grape varieties and market acceptance: an analysis based mostly on experimental economics. OENO One 52, 247–263 (2018).
Mian, G., Nassivera, F., Sillani, S. & Iseppi, L. Grapevine resistant cultivars: a narrative evaluate and the significance on the associated wine consumption inclination. Sustainability 15, 390 (2022).
Pedneault, Ok. & Provost, C. Fungus resistant grape varieties as an appropriate different for natural wine manufacturing: advantages, limits, and challenges. Sci. Hortic. 208, 57–77 (2016).
Google Scholar
Woźniak-Gientka, E. et al. Public notion of plant gene applied sciences worldwide within the mild of meals safety. GM Crops Meals 13, 218–241 (2022).
