{"id":3422,"date":"2026-08-07T12:51:00","date_gmt":"2026-08-07T12:51:00","guid":{"rendered":"https:\/\/futurenews24.com\/index.php\/2026\/08\/07\/utm_campaignrss-30\/"},"modified":"2026-08-07T16:59:04","modified_gmt":"2026-08-07T16:59:04","slug":"utm_campaignrss-30","status":"publish","type":"post","link":"https:\/\/futurenews24.com\/index.php\/2026\/08\/07\/utm_campaignrss-30\/","title":{"rendered":"Replimune, Alzheimer&#8217;s tau, Medicare: Readout Publication"},"content":{"rendered":"<p><br \/>\n<br \/><img decoding=\"async\" src=\"https:\/\/www.statnews.com\/wp-content\/uploads\/2025\/05\/https___arcmigration-prdweb.bostonglobe.com_r_Boston_2011-2020_2020_01_24_BostonGlobe.com_Business_Images_ryanairtraffic29spotlight-1024x576.jpg\" \/><\/p>\n<div>\n<p class=\"wp-block-paragraph\">Need to keep on high of the science and politics driving biotech right this moment?\u00a0Enroll\u00a0to get our biotech e-newsletter in your inbox.<\/p>\n<p class=\"wp-block-paragraph\">Boston\u2019s biotech identification is beneath stress as founders decamp for California, Alzheimer\u2019s researchers uncover extra secrets and techniques of tau operate, and Replimune lastly secures a hard-fought FDA approval.<\/p>\n<p class=\"wp-block-paragraph\">Soundtrack of this Readout: This \u201csummary funk from the flip of the century\u201d playlist. Additionally fairly helpful whereas breaking down cardboard packing containers and covertly tossing child artwork initiatives.<\/p>\n<h2 id=\"h-replimune-finally-wins-battle-for-fda-approval\" class=\"wp-block-heading\">Replimune lastly wins battle for FDA approval<\/h2>\n<p class=\"wp-block-paragraph\">After two rejections and a unprecedented third evaluate, the FDA has granted accelerated approval to Replimune\u2019s melanoma remedy RP1 \u2014 a call\u00a0that means\u00a0regulators are making use of a extra versatile strategy to most cancers drug critiques, regardless of lingering issues from FDA employees concerning the underlying knowledge. The record worth of the drug, Tudriqev, shall be $450,000 per course of remedy earlier than rebates and reductions. <\/p>\n<p class=\"wp-block-paragraph\">\u201cWe anticipate sturdy demand for the routine given its relative ease of entry and benign security profile,\u201d stated Leerink biotech analyst Daina Graybosch in a analysis word final week.<\/p>\n<p class=\"wp-block-paragraph\">Regardless of issues from former FDA oncology chief Richard Pazdur through the approval bid final yr, the company\u2019s advisers in the end concluded that the remedy\u2019s obvious advantages for sufferers who&#8217;ve exhausted PD-1 inhibitors outweighed any flaws within the single-arm trial.<\/p>\n<p class=\"wp-block-paragraph\">Learn extra.<\/p>\n<h2 id=\"h-boston-is-giving-up-ground-to-sf\" class=\"wp-block-heading\">Boston is giving up floor to SF<\/h2>\n<p class=\"wp-block-paragraph\">Boston retains insisting it\u2019s the biotech capital of the world, and it nonetheless has an excellent case to make. But it surely\u2019s additionally\u00a0onerous to disregard founders who had been generated there however determined it\u2019s time to go away.<\/p>\n<p class=\"wp-block-paragraph\">Felix Wong grew up in Massachusetts, earned levels from Harvard, educated at MIT, and nonetheless concluded Silicon Valley supplied one thing Boston couldn\u2019t: traders keen to wager on formidable younger individuals earlier than they&#8217;d grey hair. <\/p>\n<p class=\"wp-block-paragraph\">\u201cThere\u2019s some loopy experiments that we\u2019re at the moment working \u2026\u00a0that I most likely wouldn&#8217;t have thought of once I was in Boston,\u201d Wong stated.<\/p>\n<p class=\"wp-block-paragraph\">His firm, Built-in Biosciences, is only one startup, but it surely embodies a broader nervousness hanging over Massachusetts as AI reshapes biotech.<\/p>\n<p class=\"wp-block-paragraph\">Learn extra from The Boston Globe\u2019s Emma Platoff.<\/p>\n<h2 id=\"h-tau-s-dark-side-points-toward-new-treatments\" class=\"wp-block-heading\">Tau\u2019s darkish facet factors towards new therapies<\/h2>\n<p class=\"wp-block-paragraph\">Tau has lengthy been thought of one in all Alzheimer\u2019s most necessary culprits, however Stanford researchers have now uncovered what could also be one of many protein\u2019s most damaging tips, a brand new Neuron paper reveals. The protein appears to power electrons to run backward via mitochondria, triggering oxidative stress, irritation, and neuronal damage, STAT\u2019s Jonathan Wosen writes.<\/p>\n<p class=\"wp-block-paragraph\">In mice, flies, and human neurons, blocking this reverse electron transport diminished neurodegeneration and improved reminiscence \u2014 elevating the potential of a completely new therapeutic technique. The work\u2019s impressed a startup, Cerepeut, to develop small molecule medicine geared toward stopping the method earlier than neurons succumb.<\/p>\n<p class=\"wp-block-paragraph\">Learn extra.<\/p>\n<h2 id=\"h-subtle-medicare-policy-shift-could-delay-drug-price-negotiations\" class=\"wp-block-heading\">Delicate Medicare coverage shift might delay drug worth negotiations<\/h2>\n<p class=\"wp-block-paragraph\">A delicate Trump administration coverage change could have handed AbbVie years of further pricing energy, STAT\u2019s Ed Silverman writes. A brand new evaluation from Public Citizen argues CMS reset the clock for a slender class of biologic medicine that had been initially accredited as conventional medicine earlier than being reclassified. <\/p>\n<p class=\"wp-block-paragraph\">This delayed the date by which AbbVie\u2019s blockbuster pancreatic enzyme drug Creon would possibly grow to be eligible for Medicare worth negotiations \u2014 pushing Creon\u2019s eligibility again seven years regardless of costing the federal program $1.5 billion yearly. The group contends the reinterpretation runs counter to Congress\u2019s intent, prices taxpayers cash, and will in the end profit different corporations \u2014 together with Novo Nordisk and doubtlessly Eli Lilly \u2014 if extra medicine are later reclassified as biologics.<\/p>\n<p class=\"wp-block-paragraph\">Learn extra.<\/p>\n<h2 id=\"h-more-reads\" class=\"wp-block-heading\">Extra reads<\/h2>\n<p>Braveheart fees previous expectations with $382.5 million IPO to fund cardio drug from Hengrui, FierceBiotech<\/p>\n<p>FDA outlines expedited IND pilot plans, searching for to choose as much as 10 applications by year-end, Endpoints<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.statnews.com\/2026\/08\/07\/biotech-news-boston-kendall-square-losing-ground-in-sf\/?utm_campaign=rss\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Need to keep on high of the science and politics driving biotech right this moment?\u00a0Enroll\u00a0to get our biotech e-newsletter in your inbox. Boston\u2019s biotech identification is beneath stress as founders decamp for California, Alzheimer\u2019s researchers uncover extra secrets and techniques of tau operate, and Replimune lastly secures a hard-fought FDA approval. Soundtrack of this Readout: [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3424,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/www.statnews.com\/wp-content\/uploads\/2025\/05\/https___arcmigration-prdweb.bostonglobe.com_r_Boston_2011-2020_2020_01_24_BostonGlobe.com_Business_Images_ryanairtraffic29spotlight-1024x576.jpg","fifu_image_alt":"","jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"jnews_override_bookmark_settings":[],"jnews_social_meta":[],"jnews_override_counter":[],"footnotes":""},"categories":[10],"tags":[3809,3810,212,263,3808,2776],"class_list":["post-3422","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biotechnology","tag-alzheimers","tag-medicare","tag-newsletter","tag-readout","tag-replimune","tag-tau"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - 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