{"id":2201,"date":"2026-07-11T00:00:00","date_gmt":"2026-07-11T00:00:00","guid":{"rendered":"https:\/\/futurenews24.com\/index.php\/2026\/07\/11\/s41433-026-04729-1\/"},"modified":"2026-07-11T20:59:14","modified_gmt":"2026-07-11T20:59:14","slug":"s41433-026-04729-1","status":"publish","type":"post","link":"https:\/\/futurenews24.com\/index.php\/2026\/07\/11\/s41433-026-04729-1\/","title":{"rendered":"Human stromal corneal lenticule implantation for refractory full-thickness macular holes: surgical method and preliminary outcomes"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div id=\"Sec3-content\">\n<p>Anatomical closure was achieved in all circumstances at 1-month follow-up. (Fig.\u00a01) Intraoperative and postoperative OCT confirmed secure lenticule integration, constantly exhibiting a hyperreflective subfoveal band and full 360\u00b0 protection beneath the retinal edges. (Fig.\u00a02) No intraoperative or early postoperative issues had been noticed. These findings counsel early structural integration with secure retinal structure at short-term follow-up.<\/p>\n<div class=\"c-article-section__figure js-c-reading-companion-figures-item\" data-test=\"figure\" data-container-section=\"figure\" id=\"figure-1\" data-title=\"Representative case.\">\n<figure><figcaption>Fig. 1: Consultant case.<\/figcaption><div class=\"c-article-section__figure-content\">\n<div class=\"c-article-section__figure-item\"><img decoding=\"async\" aria-describedby=\"figure-1-desc\" src=\"https:\/\/media.springernature.com\/lw685\/springer-static\/image\/art%3A10.1038%2Fs41433-026-04729-1\/MediaObjects\/41433_2026_4729_Fig1_HTML.png\" alt=\"Fig. 1: Representative case.\" loading=\"lazy\" width=\"685\" height=\"206\"\/><\/div>\n<div class=\"c-article-section__figure-description\" data-test=\"bottom-caption\" id=\"figure-1-desc\">\n<p>Preoperative and postoperative OCT imaging demonstrating profitable hSCL positioning and macular gap closure.<\/p>\n<\/div>\n<\/div>\n<\/figure>\n<\/div>\n<div class=\"c-article-section__figure js-c-reading-companion-figures-item\" data-test=\"figure\" data-container-section=\"figure\" id=\"figure-2\" data-title=\"Intraoperative view.\">\n<figure><figcaption>Fig. 2: Intraoperative view.<\/figcaption><div class=\"c-article-section__figure-content\">\n<div class=\"c-article-section__figure-item\"><img decoding=\"async\" aria-describedby=\"figure-2-desc\" src=\"https:\/\/media.springernature.com\/lw685\/springer-static\/image\/art%3A10.1038%2Fs41433-026-04729-1\/MediaObjects\/41433_2026_4729_Fig2_HTML.png\" alt=\"Fig. 2: Intraoperative view.\" loading=\"lazy\" width=\"685\" height=\"362\"\/><\/div>\n<div class=\"c-article-section__figure-description\" data-test=\"bottom-caption\" id=\"figure-2-desc\">\n<p>Intraoperative OCT confirming appropriate submacular positioning of the hSCL. The white sq. signifies a magnified view of the foveal area and the white arrow highlights the lenticule throughout the macular gap.<\/p>\n<\/div>\n<\/div>\n<\/figure>\n<\/div>\n<p>These outcomes help the feasibility of hSCL implantation in rFTMH. Whereas earlier studies have explored heterogeneous purposes of lenticule implantation, this strategy focuses on the standardisation of a refined surgical method particularly for refractory macular holes. In contrast with amniotic membrane\u2013based mostly approaches, stromal lenticules might supply a extra structurally secure scaffold derived from native ocular stroma, probably favouring extra constant tissue integration.<\/p>\n<p>This strategy introduces a biologically derived stromal scaffold, probably increasing present surgical methods past purely mechanical closure. Future developments might embody the usage of stromal lenticules derived from residing donors inside devoted tissue banking platforms, enabling standardised and probably bioengineered purposes.<\/p>\n<p>Supplemental materials is accessible at Eye\u2019s web site.<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.nature.com\/articles\/s41433-026-04729-1\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anatomical closure was achieved in all circumstances at 1-month follow-up. (Fig.\u00a01) Intraoperative and postoperative OCT confirmed secure lenticule integration, constantly exhibiting a hyperreflective subfoveal band and full 360\u00b0 protection beneath the retinal edges. (Fig.\u00a02) No intraoperative or early postoperative issues had been noticed. These findings counsel early structural integration with secure retinal structure at short-term [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2203,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/media.springernature.com\/m685\/springer-static\/image\/art%3A10.1038%2Fs41433-026-04729-1\/MediaObjects\/41433_2026_4729_Fig1_HTML.png","fifu_image_alt":"","jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"jnews_override_bookmark_settings":[],"jnews_social_meta":[],"jnews_override_counter":[],"footnotes":""},"categories":[10],"tags":[2711,2715,2717,186,2713,2712,2716,2721,2720,2714,2710,2718,2719],"class_list":["post-2201","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biotechnology","tag-corneal","tag-fullthickness","tag-holes","tag-human","tag-implantation","tag-lenticule","tag-macular","tag-outcomes","tag-preliminary","tag-refractory","tag-stromal","tag-surgical","tag-technique"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human stromal corneal lenticule implantation for refractory full-thickness macular holes: surgical method and preliminary outcomes - Future News 24<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/futurenews24.com\/index.php\/2026\/07\/11\/s41433-026-04729-1\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human stromal corneal lenticule implantation for refractory full-thickness macular holes: surgical method and preliminary outcomes - Future News 24\" \/>\n<meta property=\"og:description\" content=\"Anatomical closure was achieved in all circumstances at 1-month follow-up. (Fig.\u00a01) Intraoperative and postoperative OCT confirmed secure lenticule integration, constantly exhibiting a hyperreflective subfoveal band and full 360\u00b0 protection beneath the retinal edges. (Fig.\u00a02) No intraoperative or early postoperative issues had been noticed. 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