Wednesday, September 16, 2026
No Result
View All Result
Future News 24
Advertisement
  • Home
  • AI Research
  • Platforms
  • Ethics
  • Developer AI
  • Industry
  • Data Science
  • Emerging Tech
  • Quantum
  • BioTech
  • Decentralized
  • Home
  • AI Research
  • Platforms
  • Ethics
  • Developer AI
  • Industry
  • Data Science
  • Emerging Tech
  • Quantum
  • BioTech
  • Decentralized
No Result
View All Result
Future News 24
No Result
View All Result
Home BioTechnology

Amplifying tumour antigen displays from intratumourally entrapped dendritic cells

Future News 24 by Future News 24
June 18, 2026
in BioTechnology
0 0
0
Amplifying tumour antigen displays from intratumourally entrapped dendritic cells
0
SHARES
0
VIEWS
Share on FacebookShare on Twitter


Herrera, F. G., Bourhis, J. & Coukos, G. Radiotherapy mixture alternatives leveraging immunity for the subsequent oncology follow. CA Most cancers J. Clin. 67, 65–85 (2017).

PubMed 

Google Scholar 

Demaria, S., Golden, E. B. & Formenti, S. C. Function of native radiation remedy in most cancers immunotherapy. JAMA Oncol. 1, 1325–1332 (2015).

Article 
PubMed 

Google Scholar 

McLaughlin, M. et al. Inflammatory microenvironment remodelling by tumour cells after radiotherapy. Nat. Rev. Most cancers 20, 203–217 (2020).

Article 
CAS 
PubMed 

Google Scholar 

Barker, H. E., Paget, J. T., Khan, A. A. & Harrington, Ok. J. The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence. Nat. Rev. Most cancers 15, 409–425 (2015).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Merad, M. & Salmon, H. Most cancers: a dendritic-cell brake on antitumour immunity. Nature 523, 294–295 (2015).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Chen, D. S. & Mellman, I. Oncology meets immunology: the cancer-immunity cycle. Immunity 39, 1–10 (2013).

Article 
PubMed 

Google Scholar 

Tang, M. et al. Toll-like receptor 2 activation promotes tumor dendritic cell dysfunction by regulating IL-6 and IL-10 receptor signaling. Cell Rep. 13, 2851–2864 (2015).

Article 
CAS 
PubMed 

Google Scholar 

Saxena, M., van der Burg, S. H., Melief, C. J. & Bhardwaj, N. Therapeutic most cancers vaccines. Nat. Rev. Most cancers 21, 360–378 (2021).

Article 
CAS 
PubMed 

Google Scholar 

Wculek, S. Ok. et al. Dendritic cells in most cancers immunology and immunotherapy. Nat. Rev. Immunol. 20, 7–24 (2020).

Article 
CAS 
PubMed 

Google Scholar 

Broz, M. L. et al. Dissecting the tumor myeloid compartment reveals uncommon activating antigen-presenting cells crucial for T cell immunity. Most cancers Cell 26, 638–652 (2014).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Min, Y. et al. Antigen-capturing nanoparticles enhance the abscopal impact and most cancers immunotherapy. Nat. Nanotechnol. 12, 877–882 (2017).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Wang, W. et al. Systemic immune responses to irradiated tumours by way of the transport of antigens to the tumour periphery by injected flagellate micro organism. Nat. Biomed. Eng. 6, 44–53 (2022).

Article 
CAS 
PubMed 

Google Scholar 

Teitz-Tennenbaum, S. et al. Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration. Most cancers Res. 63, 8466–8475 (2003).

CAS 
PubMed 

Google Scholar 

Choi, C. W. et al. Mixture remedy of stereotactic physique radiation remedy and immature dendritic cell vaccination for augmentation of native and systemic results. Most cancers. Res. Deal with. 51, 464–473 (2019).

Article 
CAS 
PubMed 

Google Scholar 

Baharom, F. et al. Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment. Cell. 185, 4317–4332.e15 (2022).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Giles, J. R. et al. CD8 T cells within the cancer-immunity cycle. Immunity 56, 2231–2253 (2023).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Verdijk, P. et al. Restricted quantities of dendritic cells migrate into the T cell space of lymph nodes however have excessive immune activating potential in melanoma sufferers. Clin. Most cancers Res. 15, 2531–2540 (2009).

Article 
CAS 
PubMed 

Google Scholar 

Buzas, E. I. The roles of extracellular vesicles within the immune system. Nat. Rev. Immunol. 23, 236–250 (2023).

Article 
CAS 
PubMed 

Google Scholar 

Ding, X. et al. Non-discriminating engineered masking of immuno-evasive ligands on tumour-derived extracellular vesicles enhances tumour vaccination outcomes. Nat. Nanotechnol. 20, 156–166 (2024).

Article 
PubMed 

Google Scholar 

Liu, G. et al. Micro organism-derived nanovesicles improve tumour vaccination by skilled immunity. Nat. Nanotechnol. 19, 387–398 (2024).

Article 
CAS 
PubMed 

Google Scholar 

Kalluri, R. & LeBleu, V. S. The biology, perform, and biomedical purposes of exosomes. Science 367, eaau6977 (2020).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Marar, C., Starich, B. & Wirtz, D. Extracellular vesicles in immunomodulation and tumor development. Nat. Immunol. 22, 560–570 (2021).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Vader, P., Mol, E. A., Pasterkamp, G. & Schiffelers, R. M. Extracellular vesicles for drug supply. Adv. Drug Deliv. Rev. 106, 148–156 (2016).

Article 
CAS 
PubMed 

Google Scholar 

Wiklander, O. P. B. et al. Antibody-displaying extracellular vesicles for focused most cancers remedy. Nat. Biomed. Eng. 8, 1453–1468 (2024).

Yue, Y. et al. Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered micro organism. Nat. Biomed. Eng. 6, 898–909 (2022).

Article 
CAS 
PubMed 

Google Scholar 

Ruhland, M. Ok. et al. Visualizing synaptic switch of tumor antigens amongst dendritic cells. Most cancers Cell 37, 786–799.e5 (2020).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Pitt, J. M. et al. Dendritic cell-derived exosomes for most cancers remedy. J. Clin. Make investments. 126, 1224–1232 (2016).

Article 
PubMed 
PubMed Central 

Google Scholar 

Pitt, J. M. et al. Dendritic cell-derived exosomes as immunotherapies within the struggle towards most cancers. J. Immunol. 193, 1006–1011 (2014).

Article 
CAS 
PubMed 

Google Scholar 

Mu, N. et al. Plant-derived exosome-like nanovesicles: present progress and prospects. Int. J. Nanomed. 18, 4987–5009 (2023).

Article 
CAS 

Google Scholar 

Lian, M. Q. et al. Plant-derived extracellular vesicles: latest developments and present challenges on their use for biomedical purposes. J. Extracell. Vesicles 11, e12283 (2022).

Article 
PubMed 
PubMed Central 

Google Scholar 

Wong, A. S., Che, C. M. & Leung, Ok. W. Latest advances in ginseng as most cancers therapeutics: a useful and mechanistic overview. Nat. Prod. Rep. 32, 256–272 (2015).

Article 
CAS 
PubMed 

Google Scholar 

Liu, S. et al. Structural characterization of a novel polysaccharide from Panax notoginseng residue and its immunomodulatory exercise on bone marrow dendritic cells. Int. J. Biol. Macromol. 161, 797–809 (2020).

Article 
CAS 
PubMed 

Google Scholar 

Kang, S. & Min, H. Ginseng, the ‘immunity enhance’: the consequences of panax ginseng on immune system. J. Ginseng Res. 6, 354–368 (2012).

Article 

Google Scholar 

Krawczyk, Ok. et al. Electrogenetic mobile insulin launch for real-time glycemic management in kind 1 diabetic mice. Science 368, 993–1001 (2020).

Article 
CAS 
PubMed 

Google Scholar 

Hao, Y. et al. Promotion or inhibition of extracellular vesicle launch: rising therapeutic alternatives. J. Management. Launch 340, 136–148 (2021).

Article 
CAS 
PubMed 

Google Scholar 

Mayer, A. Intracellular membrane fusion: SNAREs solely?. Curr. Opin. Cell Biol. 11, 447–452 (1999).

Article 
CAS 
PubMed 

Google Scholar 

Bennaceur, Ok. et al. Dendritic cells dysfunction in tumour surroundings. Most cancers Lett. 272, 186–196 (2008).

Article 
CAS 
PubMed 

Google Scholar 

Feng, J. et al. Plant-derived vesicle-like nanoparticles as promising biotherapeutic instruments: current and future. Adv. Mater. 35, e2207826 (2023).

Article 
PubMed 

Google Scholar 

Li, Q. et al. The mix of gemcitabine and ginsenoside Rh2 enhances the immune perform of dendritic cells towards pancreatic most cancers by way of the CARD9-BCL10-MALT1/NF-κB pathway. Clin Immunol. 248, 109217 (2023).

Article 
CAS 
PubMed 

Google Scholar 

Son, Ok. J., Choi, Ok. R., Lee, S. J. & Lee, H. Immunogenic cell loss of life induced by ginsenoside Rg3: significance in dendritic cell-based anti-tumor immunotherapy. Immune Netw. 16, 75–84 (2016).

Article 
PubMed 
PubMed Central 

Google Scholar 

Zhang, Y. et al. Useful regulation of ginsenosides on myeloid immunosuppressive cells within the tumor microenvironment. Integr. Most cancers Ther. 18, 1534735419886655 (2019).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Kalluri, R. The biology and performance of exosomes in most cancers. J. Clin. Make investments. 126, 1208–1215 (2016).

Article 
PubMed 
PubMed Central 

Google Scholar 

Mathieu, M., Martin-Jaular, L., Lavieu, G. & Théry, C. Specificities of secretion and uptake of exosomes and different extracellular vesicles for cell-to-cell communication. Nat. Cell Biol. 21, 9–17 (2019).

Article 
CAS 
PubMed 

Google Scholar 

Savina, A., Furlán, M., Vida, L. M. & Colombo, M. I. Exosome launch is regulated by a calcium-dependent mechanism in K562 cells. J. Biol. Chem. 278, 20083–20090 (2003).

Article 
CAS 
PubMed 

Google Scholar 

Messenger, S. W., Woo, S. S., Solar, Z. & Martin, T. F. J. A Ca2+-stimulated exosome launch pathway in most cancers cells is regulated by Munc13-4. J. Cell Biol. 217, 2877–2890 (2018).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

MacNabb, B. W. et al. Dendritic cells can prime anti-tumor CD8+ T cell responses by way of main histocompatibility advanced cross-dressing. Immunity 55, 2206–2208 (2022).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Pittet, M. J., Di Pilato, M., Garris, C. & Mempel, T. R. Dendritic cells as shepherds of T cell immunity in most cancers. Immunity 56, 2218–2230 (2023).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Reis e Sousa, C. Dendritic cells in a mature age. Nat. Rev. Immunol. 6, 476–483 (2006).

Article 
CAS 
PubMed 

Google Scholar 

Moon, C. Y. et al. Dendritic cell maturation in most cancers. Nat. Rev. Most cancers 25, 225–248 (2025).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Carrillo-Conde, B. et al. Mannose-functionalized ‘pathogen-like’ polyanhydride nanoparticles goal C-type lectin receptors on dendritic cells. Mol. Pharm. 8, 1877–1886 (2011).

Article 
CAS 
PubMed 

Google Scholar 

Tomura, M. et al. Monitoring and quantification of dendritic cell migration and antigen trafficking between the pores and skin and lymph nodes. Sci. Rep. 4, 6030 (2014).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Moriya, T. et al. Immunogenic tumor cell loss of life promotes dendritic cell migration and inhibits tumor progress by way of enhanced T cell immunity. iScience 24, 102424 (2021).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Shand, F. H. et al. Monitoring of intertissue migration reveals the origins of tumor-infiltrating monocytes. Proc. Natl Acad. Sci. USA 111, 7771–7776 (2014).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar 

Manno, M., Bongiovanni, A., Margolis, L., Bergese, P. & Arosio, P. The physico-chemical panorama of extracellular vesicles. Nat. Rev. Bioeng. 3, 68–82 (2025).

Article 
CAS 

Google Scholar 

Wang, S. et al. Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment. Sci. Transl. Med. 13, eabb6981 (2021).

Article 
CAS 
PubMed 

Google Scholar 

Qin, H. et al. Growth of a most cancers vaccine utilizing in vivo click-chemistry-mediated lively lymph node accumulation for improved immunotherapy. Adv. Mater. 33, e2006007 (2021).

Article 
PubMed 

Google Scholar 

Li, N. et al. Potent prophylactic most cancers vaccines harnessing floor antigens shared by tumour cells and induced pluripotent stem cells. Nat. Biomed. Eng. 9, 215–233 (2025).

Article 
CAS 
PubMed 

Google Scholar 

Gong, N. et al. Enhancing in situ most cancers vaccines utilizing supply applied sciences. Nat. Rev. Drug Discov. 23, 607–625 (2024).

Article 
CAS 
PubMed 

Google Scholar 



Source link

Tags: AmplifyingantigenCellsdendriticentrappedintratumourallypresentationstumour
Previous Post

GLM-5.2 might be essentially the most highly effective text-only open weights LLM

Next Post

[2606.16533] Kairos: A Native World Mannequin Stack for Bodily AI

Next Post
[2606.16533] Kairos: A Native World Mannequin Stack for Bodily AI

[2606.16533] Kairos: A Native World Mannequin Stack for Bodily AI

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Fetching latest news…
FUTURENEWS24
Live Feed
All
AI
Dev
Industry
Frontier
Updates in 60s
FN24 AI & Tech
View All →
Future News 24

The world's leading source for AI research, emerging technology, and the people building the future. Independent, rigorous, and always ahead.

CATEGORIES

  • AI Platforms & Apps
  • AI Research & Breakthroughs
  • BioTechnology
  • Data Science & MLOps
  • Decentralized Technology
  • Developer AI & Open-Source Ecosystem
  • Emerging Technologies & Innovations
  • Ethics & Policy
  • Industry & Business
  • Quantum Computing
  • Uncategorized

LATEST

  • [2602.13312] PeroMAS: A Multi-agent System of Perovskite Materials Discovery
  • GPT-6 Astra overview: code overview good points, privateness, and value
  • GPT-6 Astra: Options, Benchmarks, Pricing, and What’s New
  • About Us
  • Advertise with Us
  • Disclaimer
  • Privacy Policy
  • DMCA 
  • Cookie Policy
  • Terms and Conditions
  • Contact us

© 2026 Future News 24. All rights reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Home
  • AI Research
  • Platforms
  • Ethics
  • Developer AI
  • Industry
  • Data Science
  • Emerging Tech
  • Quantum
  • BioTech
  • Decentralized

© 2026 Future News 24. All rights reserved.

Website security powered by MilesWeb